Transthoracic Echocardiography to Rule Out Paroxysmal Atrial Fibrillation as a Cause of Stroke or Transient Ischemic Attack
2011 | journal article; research paper. A publication with affiliation to the University of Göttingen.
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Transthoracic Echocardiography to Rule Out Paroxysmal Atrial Fibrillation as a Cause of Stroke or Transient Ischemic Attack
Stahrenberg, R.; Edelmann, F. ; Haase, B.; Lahno, R.; Seegers, J.; Weber-Krueger, M. & Mende, M. et al. (2011)
Stroke, 42(12) pp. 3643-3645. DOI: https://doi.org/10.1161/STROKEAHA.111.632836
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- Authors
- Stahrenberg, Raoul; Edelmann, Frank ; Haase, Beatrice; Lahno, Rosine; Seegers, Jochen; Weber-Krueger, Mark ; Mende, Meinhard; Wohlfahrt, Janin; Kermer, Pawel ; Vollmann, Dirk; Hasenfuß, Gerd ; Groeschel, Klaus; Wachter, Rolf
- Abstract
- Background and Purpose-We assessed whether echocardiography can predict paroxysmal atrial fibrillation (PAF) in patients with cerebral ischemia presenting in sinus rhythm. Methods-Within the prospective Find-AF cohort, 193 consecutive patients with cerebral ischemia and sinus rhythm on presentation had evaluation of echocardiographic parameters of left atrial size and function. PAF was diagnosed by 7-day Holter monitoring. Results-In 26 patients with PAF, late diastolic Doppler (A') and tissue Doppler (a') velocities were lower whereas left atrial diameter, left atrial volume index (LAVI), LAVI/A, and LAVI/a' were larger (P < 0.05 for all) than they were in 167 patients without PAF. In multivariate models A, a', LAVI/A, and LAVI/a' predicted the presence of PAF. Area under the receiver operating characteristic curve to diagnose PAF was highest for LAVI/a' (0.813 [0.738; 0.889]). A previously suggested cut-off of LAVI/a' < 2.3 had 92% sensitivity, 55.8% specificity, and 98% negative predictive value for PAF. Conclusions-LAVI/a' < 2.3 can effectively rule out PAF in patients with cerebral ischemia. (Stroke. 2011; 42: 3643-3645.)
- Issue Date
- 2011
- Journal
- Stroke
- ISSN
- 0039-2499