Secrets of the secretome in Staphylococcus aureus
2014 | journal article
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Details
- Authors
- Kusch, Harald ; Engelmann, Susanne
- Abstract
- Secreted proteins constitute a reservoir of virulence factors. Here, an in silico analysis of the secretome of 15 S. aureus reference strains is presented revealing that about 30% of the encoded proteome of this bacterium could be secreted. In total 1354 proteins were predicted to be localized outside the cytoplasm representing the pan-secretome of S. aureus. 41% of these proteins have been identified to be expressed using different approaches. The function of at least 50% of the secreted proteins encoded by S. aureus is not yet clear and a possible role in virulence has to be elucidated.
- Issue Date
- 2014
- Journal
- International Journal of Medical Microbiology
- ISSN
- 1438-4221
- eISSN
- 1618-0607
- Language
- English