Nanoscopy in a Living Mouse Brain

2012 | journal article; research paper. A publication with affiliation to the University of Göttingen.

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​Nanoscopy in a Living Mouse Brain​
Berning, S. ; Willig, K. I. ; Steffens, H. ; Dibaj, P.   & Hell, S. ​ (2012) 
Science, 335(6068) pp. 551​-551​.​ DOI: https://doi.org/10.1126/science.1215369 

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Authors
Berning, Sebastian ; Willig, Katrin I. ; Steffens, Heinz ; Dibaj, Payam ; Hell, Stefan 
Abstract
We demonstrated superresolution optical microscopy in a living higher animal. Stimulated emission depletion (STED) fluorescence nanoscopy reveals neurons in the cerebral cortex of a mouse with <70-nanometer resolution. Dendritic spines and their subtle changes can be observed at their relevant scales over extended periods of time.
Issue Date
2012
Journal
Science 
ISSN
0036-8075
Language
English

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